Electro-spinning of pure collagen nano-fibres – Just an expensive way to make gelatin?

Spiders spinning electrically charged nano-fibres.

Most spider threads are on the micrometre and sub-micrometre scale. Yet, there are some spiders that spin true nano-scale fibres such as the cribellate orb spider, Uloborus plumipes. Here, we analyse the highly specialized capture silk-spinning system of this spider and compare it with the silk extrusion systems of the more standard spider dragline threads. The cribellar silk extrusion system c...

Production and Characterization of Gelatine Based Electro-spun Nano-fibres as Burn Wound Dressings

Silver sulfadiazine is used to prevent and treat infections of second- and third-degree burns. It kills a wide variety of bacteria. In this study silver sulfadiazine was used in gelatin based electro-spun nano-fibers with various drug to polymer ratios (0, 5, 10, 15 and 20 %). SEM, EDX and FTIR analysis showed that the continuous, bead-free, fine fibers containing silver sulfadiazine as an anti...

Biomimetic wet-stable fibres via wet spinning and diacid-based crosslinking of collagen triple helices

One of the limitations of electrospun collagen as bone-like fibrous structure is the potential collagen triple helix denaturation in the fibre state and the corresponding inadequate wet stability even after crosslinking. Here, we have demonstrated the feasibility of accomplishing wet-stable fibres by wet spinning and diacid-based crosslinking of collagen triple helices, whereby fibre ability to...

Comparison of the Anti-Fungal Effect of Electro-Spinning Drug-Loaded Nano-Fibers and Pad Dry Drug-Loaded Fabrics

When are effective medications just too expensive?